In this study, 257 teachers in Tibetan and Qiang region of Sichuan, China, from three dimensions of basic information literacy, information integration literacy and scientific research information literacy, to understand the information literacy and basic information. Through description statistics and difference analysis, the results show that there is no significant difference in information literacy among teachers with different genders and education background. There are significant differences in teachers' information literacy in ethnic minority areas of different ages and teaching age. Based on the empirical analysis, the improvement suggestions are put forward in order to provide reference for the improvement of teachers' information literacy in ethnic minority areas.