Ability of a small firm to incorporate an Enterprise Resource Planning (ERP) system into its operations is becoming a more financially viable alternative for small firms, providing them with efficient and cost-effective management solutions. Small Medium Enterprises (SMEs) are deploying ERP systems to become more competitive, efficient, and customer-friendly as the business climate becomes tougher. However, ERP providers and implementers face certain specific challenges in the SME sector. The purpose of this study is to analyze the impact of enterprise resource planning on organizational sustainability and to explore mediating role of project management competency and spiritual intelligence on enterprise resource planning and organizational sustainability of the SME sector in Pakistan. The sample size for this study was 190, and the participants were employees of the SMEs sector in Twin cities (Islamabad and Rawalpindi) of Pakistan. The findings show that enterprise resource planning (ERP) has a significant positive impact on organizational sustainability and project management competency and spiritual intelligence play mediating roles between enterprise resource planning (ERP) and organizational sustainability.  Besides, our findings have implication for theory and practice.