Modern dentistry generates a lot of trash that could harm people and the environment. A descriptive cross-sectional study was conducted on dental surgery workers from several dental setups in Karachi. Total 90 staff from the selected facilities participated in the study. The data were collected using a systematic questionnaire and observation checklist. The survey asked about socio-demographic information and dental waste management knowledge and behaviour. Waste disposal was poorly understood, and methods did not follow global rules. All participants placed sharp waste in puncture-resistant containers; however 95.55% did not label clinical trash. Trash management education, monitoring, and awareness are critically needed.