This doctoral dissertation conducts an exhaustive geopolitical analysis to unravel the intricate relationship between United States (US) policies and asymmetrical warfare within Afghanistan's context. Asymmetrical warfare, characterized by the use of unconventional tactics by non-state actors, presents profound challenges to conventional military strategies and significantly influences regional geopolitics. The study adopts a comprehensive approach, delving into the historical, political, economic, and cultural factors that have shaped US policies and impacted the dynamics of asymmetrical warfare in Afghanistan. By synthesizing a diverse range of primary and secondary sources, including government reports, scholarly literature, and expert interviews, this research aims to provide a sophisticated understanding of how US policies have not only responded to but also shaped the deployment of asymmetrical warfare tactics in Afghanistan. The dissertation contributes invaluable insights to the fields of international relations, conflict studies, and military strategy by dissecting the nuanced geopolitical implications of these interactions. Recent geopolitical transformations, exemplified by the US withdrawal from Afghanistan, have introduced a complex security landscape marked by the resurgence of Taliban influence and evolving regional power dynamics involving influential actors such as China and Russia. This study emphasizes the urgent need to recalibrate US engagement strategies to navigate emerging geopolitical realities effectively and advance sustainable peace through inclusive dialogue and reconciliation in Afghanistan. By integrating the latest geopolitical developments, this research aims to offer policymakers astute guidance in crafting approaches that foster stability and prosperity in Afghanistan.