Novel corona virus 2019 spread in the globe and all the nations are on alert to fight against this pandemic. Since Dec 2019, total 784 cases of novel ‐CoV had been reported in Pakistan till 23 March, 2020 with 6 recoveries and 5 deaths. This cluster, has been reported in under develop country (Pakistan) mostly in the south‐western parts. The data was collected from that parts on health care worker’s awareness and attitudes towards the control of Novel ‐CoV might be helpful when health programs are arranged. A questionnaire comprising 6 demographic, 8 knowledge, 8 attitudes and 6 precautions items were given. Three hundred and thirty health workers (82.5%) responded the questions. The participant’s age range was 24–65 years. Male 58.4 % (n=193) were in majority than females 41.5% (n=137).  The participants included 29.6% (n=98) physicians, 31.8%(n=105) public health officers and 38.4% (n=127) paramedics. 55.4 % (n=183) were working in referral hospitals and 44.5% (n= 147) in primary health care centers. Most of the respondents were having experience 11-20 years 42.1% (n=139) followed by 21 & above years 37.8%(n=125) and the least were in the age 1-10 years 20% (n=66). Of the respondents 65.7% (n=217) were from urban areas and that of 34.2% (n=113) from rural health care centers.  The majority, 76.6% (n=253) were aware that the infection is a viral. Regarding mode of transmission 63.3% (n=209) were voted for its transmission due to droplets after sneezing. A majority of participants 31.2% (n=103) agreed for shortness of breath to be the symptoms, 26.6% (n=88) flu like, 23% (n=76) headache and 19% (n=63) with high temperature. In the response of question “what happens for COVID disease” 92.1% were responded that occurs flu like symptoms, 3.63% (n=12) were said for sudden death and 4.24% (n=14) were of the view that it affects the human once in life. Most of the respondents 76.3% (n=252) were agreed that more than three days it take to appear the symptoms after the infection. Majority of the respondents 74.8% (n=247) were have voted for PCR tests for diagnosis. Regarding medication 48.7% (n=161) were of the view that it can be treated with antiviral, 22.1% (n=73) by use of antibiotics, 12.4% (n=41) through antipyretic medications. In response to the question that “What resource lacking to treat patients with COV disease? 48.1% (n-159) medication needed to treat, 27.8% (n=92) sufficient training is needed, 18.1% (n=60) Instrument needed to treat, 5.75% (n=19) access to laboratory tools were responded. Of the 330 health workers 94.8% were familiar with WHO guidelines of novel corona virus. In response to the question “Can COV may prevent me from travelling” 90.9% were agreed. When asked the question “The government should restrict travel to the areas of the disease” 100 % (n=330) were of the viewed. Most of the individuals 97.2% were of the view that the government should isolate infected patients in special established hospitals. Majority of the health workers 99.3 % (n=328) were said that the government must be decide to close the schools if the number of corona cases increases. On asking the question “Can COV be treated?” 61.5% were having the opinion that CoV disease can be treated. Regarding availability of vaccination 99.6% were agreed that vaccines are available for treating the novel COV –disease. Against the question “Are there adequate resources available to treat COV disease?” 97.5% were of the view that adequate resources are not available for treating the disease. Regarding the prophylaxis of the disease 95.7% (n=316) were agreed to wash hands regularly, 71.8% were agreed that Avoiding touching the eyes, nose, and mouth, 93% agreed on the statement “Covering nose and mouth with a tissue paper when coughing or sneezing” 85.1% were agreed on the point “Throw tissue paper in the trash after use it”, 96.3% were agreed on “Use face mask to cover the mouth and nose in crowded areas, 88.1% were agreed that stop normal activities such as going to work, school, travel, shopping when symptoms appear. The health workers in Malakand region showed a high level of information and helpful attitude toward novel ‐CoV. The knowledge level was difference in between many professions about the infection. Periodic educational involvements and professional campaigns are still required. Any interventions should be directed towards the non‐physician and non‐nursing professions.