This study aimed to investigate the effects of oral administration of taurine on various cardiovascular parameters, including blood pressure, lipid profiles, inflammation markers, and vasodilation, in patients with borderline hypertension.Eighty young patients with borderline hypertension were enrolled in a double-blind, placebo-controlled study. The participants were divided into two groups: the Taurine group (n=40) and the Placebo group (n=40). The Taurine group received 6 grams of taurine daily for 12 weeks, while the Placebo group received a placebo. Baseline measurements of blood pressure, lipid profiles, inflammation markers, and vasodilation were taken before the intervention, and post-intervention measurements were recorded after 12 weeks.In this study involving individuals with borderline hypertension, oral taurine supplementation (6 g/day for 12 weeks) led to significant improvements in various cardiovascular parameters. The Taurine group (n=40), with a mean age of 48.4 years and baseline ejection fraction of 61.3%, exhibited remarkable reductions in systolic blood pressure (from 136.5 mmHg to 126.1 mmHg, p < 0.001) and diastolic blood pressure (from 80.4 mmHg to 73.3 mmHg, p < 0.001) post-intervention. Vasodilation increased from 5.4% to 7.0% (p < 0.001), indicating enhanced vascular function. Taurine supplementation also resulted in favourable lipid profile changes, with reduced total cholesterol (from 202 mg/dL to 191 mg/dL, p < 0.001), LDL cholesterol (from 127 mg/dL to 116 mg/dL, p < 0.001), triglycerides (from 156 mg/dL to 146 mg/dL, p < 0.001), and increased HDL cholesterol (from 45 mg/dL to 50 mg/dL, p < 0.001), suggesting a potential anti-atherogenic effect. Furthermore, taurine supplementation exhibited a significant anti-inflammatory effect, as evidenced by reductions in CRP (from 3.2 mg/L to 2.7 mg/L, p < 0.001) and IL-6 (from 8.4 pg/mL to 7.2 pg/mL, p < 0.001) levels.Oral administration of taurine for 12 weeks demonstrated positive effects on blood pressure, lipid profiles, inflammation markers, and vasodilation in patients with borderline hypertension. These findings suggest that taurine supplementation may hold promise as a potential intervention for improving cardiovascular health.