The study aims to assess the contamination of groundwater with some toxic heavy elements in the study area (Cr, Cu, Mn, Ni, Zn, Mo, Pb, As, Co, Fe). A total of (1200) samples were collected from 10 wells distributed in Al-Zubair district, with one sample per well per month from September 2022 to August 2023. The study found an increase in the levels of toxic heavy elements in groundwater beyond the allowable environmental limits, with the highest values recorded in the winter and spring seasons. The results of the statistical analysis showed significant differences with a probability of less than (0.05) between the selected seasons for the study. Strongly significant differences were found in some seasons, with the most prominent being the summer and winter seasons.