Immunomodulatory And Protective Effects Of Oryza Sativa Derived Arabinoxylans (Axs)

Authors

  • Naimat Ullah
  • Muhammad Kasib Khan
  • Asghar Abbas
  • Kashif Hussain
  • Atif Rehman
  • Muhammad Umair Waqas
  • Baseer Ahmad
  • Hafeez ur Rehman Ali Khera
  • Muhammad Adnan Sabir Mughal
  • Rana Muhammad Shahbakht
  • Riffat Yasin
  • Muhammad Usman
  • Muhammad Kashif
  • Mazhar Abbas
  • Tanveer Ahmad

DOI:

https://doi.org/10.53555/ks.v12i5.3197

Keywords:

Arabinoxylans, Immunity, Chicken, Oryza Sativa

Abstract

Immunomodulatory effects of rice bran (Oryza sativa)-derived arabinoxylans (AXs) were evaluated in chickens. Broiler chicks were randomly allocated into five equal groups of 25 chicks each. The humoral immune response was detected using sheep RBCs. Cellular immunity was assessed using phytohemagglutinin-P (PHA-P), concanavalin-A (Con-A), carbon clearance, and dinitrochlorobenzene (DNCB) assays. Following a 14-day course of AXs, all experimental and control groups were exposed to sporulated oocysts of mixed Eimeria species, and the anticoccidial potential was assessed based on the mortality rate, lesion score, oocysts per gram of stool (OPG), and weight of lymphoid organs on different days post infection. We observed that AXs-treated groups showed higher immunomodulatory effects. However, the group treated with AXs @ 300 mg/Kg of body weight showed higher antibodies, a higher cellular response to PHA-P and CON-A, and higher carbon clearance (P<0.05), while the group B chickens showed maximum skin thickness before and after 24 to 48 hours of DNCB dosage. This study could be useful in identifying an immunomodulatory  agent for the control of chicken coccidiosis.

Author Biographies

Naimat Ullah

Department of Parasitology, University of Agriculture Faisalabad, Pakistan

Muhammad Kasib Khan

Department of Parasitology, University of Agriculture Faisalabad, Pakistan

Asghar Abbas

Department of Parasitology, University of Agriculture Faisalabad, Pakistan

Kashif Hussain

Department of Parasitology, University of Agriculture Faisalabad, Pakistan

Atif Rehman

Department of Parasitology, University of Agriculture Faisalabad, Pakistan

Muhammad Umair Waqas

Department of Parasitology, University of Agriculture Faisalabad, Pakistan

Baseer Ahmad

Department of Parasitology, University of Agriculture Faisalabad, Pakistan

Hafeez ur Rehman Ali Khera

Department of Parasitology, University of Agriculture Faisalabad, Pakistan

Muhammad Adnan Sabir Mughal

Department of Parasitology, University of Agriculture Faisalabad, Pakistan

Rana Muhammad Shahbakht

Department of Parasitology, University of Agriculture Faisalabad, Pakistan

Riffat Yasin

Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Shareef University of agriculture Multan

Muhammad Usman

Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Shareef University of agriculture Multan

Muhammad Kashif

Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Shareef University of agriculture Multan

Mazhar Abbas

Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Shareef University of agriculture Multan

Tanveer Ahmad

Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Shareef University of agriculture Multan

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Published

2024-06-29

How to Cite

Naimat Ullah, Muhammad Kasib Khan, Asghar Abbas, Kashif Hussain, Atif Rehman, Muhammad Umair Waqas, … Tanveer Ahmad. (2024). Immunomodulatory And Protective Effects Of Oryza Sativa Derived Arabinoxylans (Axs). Kurdish Studies, 12(5), 178–184. https://doi.org/10.53555/ks.v12i5.3197

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